PSA assay used with ADVIA Centaur systems Therapeutic Goods . Consumers and health professionals are advised that Siemens Healthcare Diagnostics, in consultation with the TGA, is in the process of updating the Instructions for Use (IFU) for prostate-specific antigen (PSA) assays used with ADVIA Centaur systems. The update will clarify the utility of the PSA assay.
PDF Laboratory Procedure Manual . Complex PSA using Advia Centaur in Serum NHANES 2007-2008 . 1. SUMMARY OF TEST PRINCIPLE AND CLINICAL RELEVANCE . Prostate specific antigen (PSA) is a serine protease produced by epithelial cells of the prostate gland. The proteolytic activity of PSA is inhibited in the bloodstream by the formation of complexes with serine protease inhibitors. ADVIA Centaur XPT Immunoassay System - Siemens Healthineers USA . ** For outside of the U.S. only, as! say developed, manufactured, and sold by Siemens Healthcare Diagnostics Inc. for Ortho Clinical Diagnostics, Inc. and Grifols Diagnostic Solutions Inc. †† The ADVIA Centaur Zika Test has not been FDA cleared or approved. This test has been authorized by FDA under an EUA for use by authorized laboratories. PDF Laboratory Procedure Manual - cdc.gov . The ADVIA Centaur cPSA assay quantitatively measures complexed prostate-specific antigen (cPSA) in human serum. Free PSA present in the sample is prevented from reacting with the total PSA antibodies by incubating the sample at 37°C with a free-PSA-specific monoclonal mouse antibody (Pretreatment Reagent), which blocks the free PSA PSA Assay Advia Centaur - Prostate Cancer . The Assay used at my primary health facility is Advia Centaur - which is apparently a product of Siemens. When I hit .03 a few months back I went and got a secondary! test by Labcorp, which uses another Assay. The result was <! ;.006. Not that I'm complaining but I can't understand how my PSA could fall from .03 to .01 over the course of 6 months.
